Mohit Khera, MD, MBA, MPH, Professor of Urology and F.
Brantley Scott Chair of Urology, Baylor College of Medicine, Houston, Texas, discusses evolving understanding of testosterone therapy and cardiovascular risk.
In this 13-minute presentation, Dr.
Khera focuses on the pivotal TRAVERSE trial and the recent announcement regarding class-wide labeling changes for testosterone products.
History of CV Events and Testosterone Therapy Dr.
Khera traces the history of concern of cardiovascular risks with testosterone therapy.
He details that early studies—such as Molly Shores’ 2006 work—showed that low testosterone was associated with higher mortality, particularly due to cardiovascular events.
However, between 2010 and 2014, several flawed studies suggested that testosterone therapy could increase cardiovascular risk.
These studies prompted the FDA to issue a warning in 2015 restricting labeled indications to men with specific medical conditions, excluding age-related hypogonadism.
The TRAVERSE Trial The TRAVERSE trial launched out of these concerns.
This large, randomized, placebo-controlled trial enrolled over 5,200 men aged 45 to 80 with low testosterone levels and existing cardiovascular risk.
Over a mean follow-up of 33 months, the trial found no increase in cardiovascular events among men treated with testosterone compared to placebo.
Importantly, no increased risk of prostate cancer or worsening of lower urinary tract symptoms was observed.
TRAVERSE Trial Update in 2025 As a result, in February 2025, the FDA updated the labeling for testosterone products.
While maintaining existing restrictions around age-related use, the FDA removed language from the Black Box related to increased risk of cardiovascular outcomes.
The FDA now requires inclusion of TRAVERSE results in labeling.
Following Ambulatory Blood Pressure Monitoring (ABPM) studies, the FDA requires product-specific information on increased blood pressure for testosterone products with completed ABPM studies.
This is in addition to warnings about increased blood pressure across all testosterone products that currently lack such warnings.
Dr.
Khera emphasizes the clinical impact of these changes.
He notes that previous warnings led many high-risk men to avoid testosterone therapy despite potential benefits.
He advocates for further research into the role of testosterone normalization in reducing cardiovascular risk.
He also encourages a reevaluation of lingering concerns around prostate health.
It can be a source of embarrassment and frustration for those who struggle with it, leading many to seek out alternative solutions to traditional medication. As soon as they approached, they heard a few slight wind noises. Erectile dysfunction (ED) is a common problem that affects millions of men around the world. If this is on the battlefield, do you want to talk about rights with your enemy Lin Feng kicked Wang Yanbing s body backwards. One such solution that has gained popularity in recent years is ED gummies – chewable supplements that claim to help improve erectile function. If he ran to save people at this time, not only would he not be able to save people, but he would also be dead.
To find out, we’ve gathered user testimonials and experiences from men who have tried them. s First update The blood jade is placed on the stone cutting table, and the blood is flowing. In this article, we’ll explore what these men have to say about their experiences with ED gummies, including any benefits or drawbacks they may have encountered. But do these ED gummies actually work? Manager Wang s words shocked all the sales staff and left them speechless. Words come.
John’s Experience:
He was skeptical at first, but after taking them for a few weeks, he noticed a significant improvement in his ability to achieve and maintain an erection. I once said that my Xia Yan s man must be better than me. Today you I did it, and I have a crush on you, so I want you to be my boyfriend. John, a 45-year-old man, had been struggling with ED for several years before deciding to try ED gummies. Then, the two men raised their heads and glanced fiercely at the hostages in front of them, and said sternly Be smart, whoever causes trouble next time, don t be so cruel, brothers. John was pleasantly surprised by the results and found that the gummies were easy to incorporate into his daily routine. If you get addicted to playing, you may lose everything. Mom, don t worry, I will run business with the boss with peace of mind from now on. Bioscience Male Enhancement Gummies Benefits And Reviews.
John also noted that the gummies helped improve his overall sexual satisfaction, leading to a more fulfilling and enjoyable experience for both him and his partner. What kind of brain does such a perverted training method need to be able to figure it out In fact, not only the seven members of the team had such an idea, but even Lin Feng once thought so. One of the main benefits that John experienced was increased confidence in the bedroom. It s really convenient. Ye Tian sat cross legged on the bed, picked up the jade tablet, and began to carve the runes. He no longer felt anxious or self-conscious about his performance, which had been a significant source of stress for him in the past. Soon, all fifty or sixty people here died in the hands of Lin Feng Hear the fire of gunfire The Phoenix team hurried towards the gate and gathered with Lin Feng, and the foreign devil who had just entered the elevator ran over here with a few people.
While they initially worked well for him, he found that he needed to take higher doses to achieve the same results after a few months. Lin Feng said warmly. Bitch, if you dare to talk nonsense, I will definitely break your legs. John ultimately decided to switch to a different form of treatment for his ED, but he was grateful for the positive impact that the gummies had on his sex life. When he heard the sound, Lin Feng s ears moved, and just from the direction of the sound, he had already identified the location of the person. However, John did mention that the effects of the gummies seemed to diminish over time. Ye Tian also returned home with the box in both hands. In the evening, Ye Ma cooked a big meal, including brown sugar pork ribs, sweet and sour seabass, braised screw shrimp, green pepper and potato shreds, and winter melon pork ribs soup.
Michael’s Testimonial:
Michael, a 55-year-old man, had been hesitant to try ED gummies but eventually decided to give them a shot after hearing positive reviews from friends. He was pleasantly surprised by how quickly he noticed a difference after starting the gummies, experiencing stronger and longer-lasting erections within just a few days.
Michael also appreciated the natural ingredients used in the gummies, as he was trying to avoid prescription drugs whenever possible. But how does this Thai boxer know that he is the cannon fodder in Lin Feng s mouth, and everything Liu Hao promised him is just empty words, just a fuse for the next match. He liked that he didn’t have to worry about timing his doses or dealing with any unpleasant side effects like he had with other medications. You and I will spread out now. When you act, try to lower your head as much as possible, and let them find out as late as possible. One of the main benefits that Michael found with the gummies was the convenience of taking them. Mood Gummies For Sex Enhancing Your Intimate Moments.
Despite his positive experience, Michael did mention that the gummies were not a perfect solution for his ED. A few drops of blood were already flowing out of his mouth, and he swallowed the rest of the blood. Overall, however, Michael was satisfied with the results he saw from the gummies and planned to continue using them as part of his treatment plan. Su Yuxin on the side could clearly feel it. Even though she was covered with an air conditioned quilt, she was still shivering from the cold. While they helped improve his erectile function, he still occasionally experienced difficulties, especially during times of high stress or fatigue. Ye Tian turned around and got into a taxi. Let s go. The taxi driver looked at Ye Tian in awe. Sir, you are so awesome.
David’s Feedback:
David was pleasantly surprised by how effective the gummies were for him, noting a significant improvement in his ability to achieve and maintain an erection. got up. Ye Tian s reaction made Han Dong a little confused. He was stunned, then looked at Ye Tian and said, I won t mince words. I like Sister Xia. David, a 35-year-old man, had struggled with ED for several years before discovering ED gummies. Oriental, you want to kill me just because of this rubbish, you are really dreaming. He was initially hesitant to try them, but after reading about the positive experiences of other men, he decided to give them a chance. Let me think about this. Lin Feng replied casually.
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One of the main benefits that David found with the gummies was the lack of side effects. Village Chief, you are finally here. The robbers were lying on the ground and immediately breathed a sigh of relief when they saw the arrival of the villagers. David also appreciated the discreet packaging of the gummies, which allowed him to take them without drawing attention or having to explain his condition to others. Unlike other medications he had tried in the past, he didn’t experience any negative reactions or discomfort when taking the gummies. Tang Xinyi said coldly. Tang Xinyi s eyes also became sharp at this moment.
Despite these drawbacks, David was overall pleased with the results he saw and planned to continue using the gummies as part of his treatment regimen. The club suddenly fell silent. Everyone looked at Duan Changfeng who was kneeling on the ground, and Ye Tian who was standing aside with a calm expression. However, David did note that the gummies were not a quick fix for his ED. Go away quickly. If someone sees you, throw him away. He s dead. Gao Hao s younger brothers did not dare to stay at the wedding banquet for one more minute and immediately carried Gao Hao away. While they worked well for him, he found that consistent use was necessary to maintain their effects. What the security officer surnamed Fang does not understand is, shouldn t the meeting be in the conference room The security officer surnamed Fang thought so, he walked to a chair in front of the middle aged bureau seat and sat down. David also mentioned that the cost of the gummies was a concern for him, as they were not covered by his insurance and could be expensive to purchase regularly. She couldn t help but ask herself, could it be that she fell in love with this perverted man.
Ben’s Review:
He was skeptical of ED gummies at first but decided to give them a try based on the recommendation of his doctor. Saucy girls, let you chat now, wait for you to drink and see how I treat you, the handsome young man s eyes show a conspiracy success, the fire in his heart can no longer be suppressed, put the wine glass It was sent to Ouyang Qian. Ben, a 50-year-old man, had tried various treatments for his ED over the years with mixed results. An inexplicable fear engulfed him in layers Surrounded, the leader bald head shrank his eyes, he raised his right hand and plunged towards Lin Feng. Ben was pleasantly surprised by how well the gummies worked for him, noticing a significant improvement in his sexual performance and overall satisfaction.
He liked that he could take them discreetly whenever he needed them, without having to plan around a specific schedule or deal with any unpleasant side effects. As long as the salary is not cut, it will be fine. At most, we can get a new job by then. One of the main benefits that Ben found with the gummies was their convenience and ease of use. Only if they are accurate will you pass the test. Otherwise, if any measurement is wrong, you have to hold Xiaoli face to face. Ben also appreciated the natural ingredients used in the gummies, as he preferred to avoid prescription medications whenever possible. This method is good or not, but it s a bad way to play, and it will cost him his life.
Ben also noted that the cost of the gummies could be prohibitive for some men, as they were not covered by insurance and could add up over time. Despite his positive experience, Ben did mention that the gummies were not a perfect solution for his ED. While they helped improve his erectile function, he still occasionally experienced difficulties, especially during times of high stress or fatigue. Not close up. Of course, everyone loves beauties. Overall, however, Ben was satisfied with the results he saw from the gummies and planned to continue using them as part of his treatment plan. Blue Gummies For Ed In Canada Detailed User Reviews And Effectiveness.